Brand Names: Anexsia, Hycet, Lorcet, Lorcet Plus, Lortab, Maxidone, Norco, Stagesic, Verdrocet, Vicodin, Vicodin ES, Vicodin HP, Xodol, Zamicet, Zolvit, Zydone
Hydrocodone-Acetaminophen combination is used to relieve moderate to moderately severe pain. Acetaminophen is used to relieve pain and reduce fever in patients. Acetaminophen may cause other unwanted effects when taken in large doses, including liver damage.
Hydrocodone is an opioid medication. It belongs to the group of medicines called narcotic analgesics (pain medicines). Hydrocodone acts on the central nervous system (CNS) to relieve pain, and stops or prevents cough.
When hydrocodone is used for a long time, it may become habit-forming, causing mental or physical dependence. However, people who have continuing pain should not let the fear of dependence keep them from using narcotics to relieve their pain. Mental dependence (addiction) is not likely to occur when narcotics are used for this purpose. Physical dependence may lead to withdrawal side effects if treatment is stopped suddenly. However, severe withdrawal side effects can usually be prevented by gradually reducing the dose over a period of time before treatment is stopped completely. Hydrocodone-Acetaminophen is available only with a doctor’s prescription.
Hydrocodone-Acetaminophen is available in these forms:
Common side effects of Hydrocodone-Acetaminophen are:
Other important side effects include:
- spasm of the ureter, which can lead to difficulty in urinating.
Hydrocodone can impair thinking and the physical abilities required for driving or operating machinery. Hydrocodone can depress breathing, and should be used with caution in elderly, debilitated patients and in patients with serious lung disease.
Hydrocodone may be habit forming. Mental and physical dependence can occur but are unlikely when used for short-term pain relief.
Acetaminophen can cause severe liver failure if excessive amounts are used and when combined with chronic alcohol use or other drugs that also impair liver function.
Hydrocodone-Acetaminophen may be habit-forming. If you feel that the medicine is not working as well, do not use more than your prescribed dose.
Check with your doctor right away if you have pain or tenderness in the upper stomach, pale stools, dark urine, loss of appetite, nausea, unusual tiredness or weakness, or yellow eyes or skin. These could be symptoms of a serious liver problem.
Serious skin reactions can occur with this medicine. Check with your doctor right away if you have blistering, peeling, or loose skin, red skin lesions, severe acne or skin rash, sores or ulcers on the skin, or fever or chills while you are using this medicine.
This medicine may cause a serious type of allergic reaction called anaphylaxis. Anaphylaxis can be life-threatening and requires immediate medical attention. Call your doctor right away if you have a rash, itching, hoarseness, trouble breathing, trouble swallowing, or any swelling of your hands, face, or mouth while you are using this medicine.
This medicine may make you dizzy, drowsy, or lightheaded. Make sure you know how you react to this medicine before you drive, use machines, or do anything else that could be dangerous if you are dizzy or not alert.
DRUG CLASS AND MECHANISM: Hydrocodone is a narcotic pain-reliever and a cough suppressant, similar to codeine. Hydrocodone blocks the receptors on nerve cells in the brain that give rise to the sensation of pain.Acetaminophen is a non-narcotic analgesic (pain reliever) and antipyretic (fever reducer). Acetaminophen works by elevating the threshold to pain, that is, in order for pain to be felt, greater stimulation of the nerves responsible for the sensation of pain is necessary. It reduces fever through its action on the temperature-regulating center of the brain. Frequently, hydrocodone and acetaminophen are combined to achieve pain relief, as in Vicodin and Lortab. The FDA approved Vicodin in January 1983.
OVERDOSE: If overdose is suspected, contact a poison control center or emergency room immediately. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include: nausea, vomiting, unusual sweating, slow breathing, slow heartbeat, loss of consciousness.